GERMINAL-CELL LOSS IN NORMAL METAZOAN SPERMATOGENESIS
نویسندگان
چکیده
منابع مشابه
MUC1 in normal and impaired spermatogenesis.
The MUC1 mucin [also known as episialin, epithelial membrane antigen (EMA) or polymorphic epithelial mucin (PEM)] is a component of the mucosal glycocalyx, contributing to anti-adhesive and protective cell functions. MUC1 has been shown in a variety of epithelial cell types in the reproductive tracts of males and females, but this is the first report of its expression in human testis and non-ep...
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How introns are lost from eukaryotic genomes during evolution remains an enigmatic question in biology. By comparative genome analysis of five Caenorhabditis and eight Drosophila species, we found that the likelihood of intron loss is highly influenced by the degree of sequence homology at exon-intron junctions: a significant elevated degree of microhomology was observed for sequences immediate...
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BACKGROUND Asexuality has major theoretical advantages over sexual reproduction, yet newly formed asexual lineages rarely endure. The success, or failure, of such lineages is affected by their mechanism of origin, because it determines their initial genetic makeup and variability. Most previously described mechanisms imply that asexual lineages are randomly frozen subsamples of a sexual populat...
متن کاملPositive selection of tyrosine loss in metazoan evolution.
John Nash showed that within a complex system, individuals are best off if they make the best decision that they can, taking into account the decisions of the other individuals. Here, we investigate whether similar principles influence the evolution of signaling networks in multicellular animals. Specifically, by analyzing a set of metazoan species we observed a striking negative correlation of...
متن کاملComment on "Positive selection of tyrosine loss in metazoan evolution".
Tan et al. (Reports, 25 September 2009, p. 1686) argued that loss of tyrosine residues from proteins in metazoans was driven by positive selection to remove potentially deleterious phosphorylation sites. We challenge this hypothesis, providing evidence that the high guanine-cytosine (GC) content of metazoan genomes was the primary driver in the loss of tyrosine residues.
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ژورنال
عنوان ژورنال: Reproduction
سال: 1973
ISSN: 1470-1626,1741-7899
DOI: 10.1530/jrf.0.0350339